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. 2018 Dec;13(4):273-281.
doi: 10.26574/maedica.2018.13.4.273.

Diseases of Civilization - Cancer, Diabetes, Obesity and Acne - the Implication of Milk, IGF-1 and mTORC1

Victor Gabriel Clatici  1 , Cristiana Voicu  1 , Catalina Voaides  2 , Anca Roseanu  3 , Madalina Icriverzi  3 , Stefana Jurcoane  2
Affiliations

Diseases of Civilization - Cancer, Diabetes, Obesity and Acne - the Implication of Milk, IGF-1 and mTORC1

Victor Gabriel Clatici et al. Maedica (Bucur). 2018 Dec.

Abstract

Nutrition and food are one of the most complex aspects of human lives, being influenced by biochemical, psychological, social and cultural factors. The Western diet is the prototype of modern dietary pattern and is mainly characterized by the intake of large amounts of red meat, dairy products, refined grains and sugar. Large amounts of scientific evidence positively correlate Western diet to acne, obesity, diabetes, heart disease and cancer, the so-called "diseases of civilization". The pathophysiological common ground of all these pathologies is the IGF-1 and mTORC pathways, which will be disscussed further in this paper.

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