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. 2018 Winter;11(Suppl 1):S14-S19.

Evaluation of the cardiovascular risk in patients with biliary stones: a descriptive cross-sectional study

Shermin Seddighi  1 , Mohammad Esmaiel Ghidari  1 , Amir Sadeghi  2 , Mohammad Amin Shahrbaf  3 , Mohammad Amin Mahmanzar  4 , Saeede Saadati  2 , Zahra Yari  2
Affiliations

Evaluation of the cardiovascular risk in patients with biliary stones: a descriptive cross-sectional study

Shermin Seddighi et al. Gastroenterol Hepatol Bed Bench. 2018 Winter.

Abstract

Aim: the aim of this study was evaluating the risk of cardiovascular disease in patients with gallstones.

Background: Gallstones is the most common Biliary System disorder which its prevalence is increasing. On other hand, cardiovascular disease is the most common cause of mortality in the world. The causes and risk factors of cardiovascular diseases and gallstones are in common.

Methods: In this descriptive cross-sectional study, patient with gallstones who hospitalized in Taleghani Hospital of Shahid Beheshti University of medical sciences or referred to its clinics in 2017, shared their demographic information and their underlying diseases with us. In addition, more data was collected with clinical examination, blood test, echocardiography and ultrasonography. Data was analyzed by SPSS vs21 software. In addition, online software was used for calculating Framingham and ASCVD risk score for cardiovascular diseases.

Results: 105 patients with gallstones and 105 healthy people participated in this study. There was no significant difference between these two groups for existence of main risk factors, but the average amount of ALT, AST, and ALP enzymes in patients with gallstones were significantly more than the control group (P value<0.05). The average amount of Framingham score was not significantly different between these two groups and the average score of ASCVD was statistically lower in our case group.

Conclusion: The risk of cardiovascular disease in patients with gallstones is not significantly more than the general population.

Keywords: Cardiovascular disease; Gallstones; Risk factors.

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