Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Sep;4(3):114-117.
doi: 10.1016/j.afos.2018.09.002. Epub 2018 Sep 26.

Sarcopenia affects conservative treatment of osteoporotic vertebral fracture

Hiroki Iida  1 , Yoshihito Sakai  1 , Tsuyoshi Watanabe  1 , Hiroki Matsui  1 , Marie Takemura  1 , Yasumoto Matsui  1 , Atsushi Harada  1 , Tetsuro Hida  2 , Kenyu Ito  3 , Sadayuki Ito  3
Affiliations

Sarcopenia affects conservative treatment of osteoporotic vertebral fracture

Hiroki Iida et al. Osteoporos Sarcopenia. 2018 Sep.

Abstract

Objectives: Sarcopenia and osteoporosis affects activities of daily living and quality of elderly people. However, little is known about its impact on elderly locomotor diseases, such as osteoporotic vertebral fracture (OVF). There is no report investigating the influence of both sarcopenia and osteoporosis on outcomes of OVF. This study aimed to evaluate the clinical outcomes of OVF in elderly patients from sarcopenic perspectives.

Methods: This prospective study was conducted with 396 patients, aged 65 years or more, hospitalized for the treatment of OVF (mean age, 81.9 ± 7.1 years; 111 males, 285 females). The primary outcome was the Japanese Orthopaedic Association (JOA) score for lumbar disease (at first visit, hospital discharge, and 1 year after treatment) and Barthel index (at the same time and before hospitalization). The second outcome was living place after discharge. Susceptibility to sarcopenia and osteoporosis were evaluated and clinical results of conservative treatment were compared.

Results: Sarcopenia significantly affected Barthel index at first visit and discharge. Sarcopenia patients had significantly higher rate for discharge to nursing home and living in nursing home after 1 year than patients without sarcopenia. Osteoporosis significantly affected the JOA score at the first visit and the Barthel index before hospitalization, at the first visit, discharge, and after 1 year. Osteoporosis did not affect the living place at discharge and after 1 year.

Conclusions: Sarcopenia and osteoporosis affected outcomes of conservative treatment for OVF; moreover, sarcopenia affected the living place of OVF patients at discharge and after 1 year.

Keywords: Conservative treatment; Sarcopenia; Vertebral fracture.

PubMed Disclaimer

References

    1. Epidemiologic and methodologic problems in determining nutritional status of older persons. Proceedings of a conference. Albuquerque, New Mexico, October 19-21, 1988. Am J Clin Nutr. 1989;50(5 Suppl):1121–1235. - PubMed
    1. Coin A., Perissinotto E., Enzi G., Zamboni M., Inelmen E.M., Frigo A.C. Predictors of low bone mineral density in the elderly: the role of dietary intake, nutritional status and sarcopenia. Eur J Clin Nutr. 2008;62:802–809. - PubMed
    1. Hida T., Ishiguro N., Shimokata H., Sakai Y., Matsui Y., Takemura M. High prevalence of sarcopenia and reduced leg muscle mass in Japanese patients immediately after a hip fracture. Geriatr Gerontol Int. 2013;13:413–420. - PubMed
    1. Hida T., Shimokata H., Sakai Y., Ito S., Matsui Y., Takemura M. Sarcopenia and sarcopenic leg as potential risk factors for acute osteoporotic vertebral fracture among older women. Eur Spine J. 2016;25:3424–3431. - PubMed
    1. Japanese Orthopaedic Association Criteria on the evaluation of the treatment of low back pain. J Jpn Orthop Assoc. 1986;60:391–394.

LinkOut - more resources