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Review
. 2019 May;244(8):655-662.
doi: 10.1177/1535370219830997. Epub 2019 Feb 18.

Choline transport for phospholipid synthesis: An emerging role of choline transporter-like protein 1

Vera Hedtke  1 , Marica Bakovic  1
Affiliations
Review

Choline transport for phospholipid synthesis: An emerging role of choline transporter-like protein 1

Vera Hedtke et al. Exp Biol Med (Maywood). 2019 May.

Abstract

This review will provide a summary of recent advances in choline transport research and highlight important novel areas of focus in the field.

Keywords: Choline; lipids; nutrition; regulation; transporters; variants.

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Figures

Figure 1.
Figure 1.
Choline transporters for betaine, acethylcholine, and phospholipid synthesis. CTLs (SLC44A1 and -2) and OCTs are widely expressed while choline transporter CHT1 in neuron-specific. Functions proposed but not confirmed are indicated (?). CDP: cytidine diphosphate; CDP-choline: citidyldiphosphocholine; CHT1: choline transporter CHT1 in neuron-specific; OCT: organic cation transporter; SLC44A: solute carriers 44 A.
Figure 2.
Figure 2.
CTL1 protein structure. The CTL1 membrane topology and features identified to be highly conserved among different species and within the SLC44A family. SLC44A: solute carriers 44 A.
See this image and copyright information in PMC

References

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