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Randomized Controlled Trial
. 2019 Dec;29(4):701-710.
doi: 10.1007/s10926-019-09831-8.

Two-Year Follow-Up of a Multi-centre Randomized Controlled Trial to Study Effectiveness of a Hospital-Based Work Support Intervention for Cancer Patients

S J Tamminga  1 , J H A M Verbeek  1   2 , M M E M Bos  3 , G Fons  4 , J J E M Kitzen  5 , P W Plaisier  6 , M H W Frings-Dresen  1 , A G E M de Boer  7
Affiliations
Randomized Controlled Trial

Two-Year Follow-Up of a Multi-centre Randomized Controlled Trial to Study Effectiveness of a Hospital-Based Work Support Intervention for Cancer Patients

S J Tamminga et al. J Occup Rehabil. 2019 Dec.

Abstract

Purpose Purpose is to: (1) study effectiveness of the hospital-based work support intervention for cancer patients at two years of follow-up compared to usual care and (2) identify which early factors predict time to return-to-work (RTW). Methods In this multi-center randomised controlled trial (RCT), 106 (self-)employed cancer patients were randomized to an intervention group or control group and provided 2 years of follow-up data. The intervention group received patient education and work-related support at the hospital. Primary outcome was RTW (rate and time) and quality of life (SF-36), and secondary outcomes were, work ability (WAI), and work functioning (WLQ). Univariate Cox regression analyses were performed to study which early factors predict time to full RTW. Results Participants were diagnosed with breast (61%), gynaecological cancer (35%), or other type of cancer (4%). RTW rates were 84% and 90% for intervention versus control group. They were high compared to national register-based studies. No differences between groups were found on any of the outcomes. Receiving chemotherapy (HR = 2.43, 95% CI 1.59-3.73 p < 0.001), low level of education (HR = 1.65, 95% CI 1.076-2.52 p = 0.02) and low work ability (HR = 1.09 [95% CI 1.04-1.17] p = 0.02) were associated with longer time to full RTW. Conclusions We found high RTW rates compared to national register-based studies and we found no differences between groups. Future studies should therefore focus on reaching the group at risk, which consist of patients who receive chemotherapy, have a low level of education and have a low work ability at diagnosis. TRIAL REGISTRATION: Netherlands Trial Registry (NTR) (http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=1658): NTR1658.

Keywords: Hospital; Neoplasms; Oncology service; Program effectiveness; Randomized controlled trial; Return to work.

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Conflict of interest statement

Authors Tamminga, Verbeek, Bos, Fons, Kitzen, Plaisier, Frings-Dresen and de Boer declare that they have no competing interest.

Figures

Fig. 1
Fig. 1
Patient flow
Fig. 2
Fig. 2
Time to return to work
See this image and copyright information in PMC

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