Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 Jul 2;220(220 Suppl 1):S5-S6.
doi: 10.1093/infdis/jiz012.

Unintended HIV-1 Transmission to a Sex Partner in a Study of a Therapeutic Vaccine Candidate

Jean-Daniel Lelièvre  1   2   3 , Laurent Hocqueloux  4
Affiliations
Case Reports

Unintended HIV-1 Transmission to a Sex Partner in a Study of a Therapeutic Vaccine Candidate

Jean-Daniel Lelièvre et al. J Infect Dis. .

Abstract

We report a case of sexual transmission of human immunodeficiency virus (HIV) that occurred during treatment discontinuation in a therapeutic vaccine trial, following oral sex. Transmission occurred even though the index participant was an HIV/AIDS activist, particularly well informed about the risks and modalities of transmission. This case report highlights the risk of secondary transmission of HIV during cessation of treatment in HIV cure-related trials.

Keywords: HIV therapeutic vaccine; analytic treatment interruption; oral sex; secondary transmission.

PubMed Disclaimer

Comment in

References

    1. Levy Y, Lelièvre J-D, Perrier A, et al. . Preliminary safety results from VRI02 ANRS 149 Light (Lipopeptide and DNA GTU HIV Therapeutic Trial) [abstract P27.09]. Presented at: HIV Research for Prevention, Chicago, Illinois, 17–21 October 2016: https://www.abstractstosubmit.com/hivr4p2016/eposter/main.php?do=YToyOnt... Accessed 18 January 2019.
    1. Lelièvre J-D. Preexposure prophylaxis for mitigating risk of HIV transmission during HIV cure–related clinical trials with a treatment interruption. J Infect Dis 2019. In this issue. - PMC - PubMed

Publication types