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Comment
. 2019 Feb 18;29(4):R128-R130.
doi: 10.1016/j.cub.2018.12.006.

Evolution: Decoy Receptors as Unique Weapons to Fight Pathogens

Wolfgang Zimmermann  1
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Evolution: Decoy Receptors as Unique Weapons to Fight Pathogens

Wolfgang Zimmermann. Curr Biol. .
Free article

Abstract

Many pathogens must bind to entry receptors on the surfaces of host cells yet avoid any closely-related phagocytic decoy receptors on granulocytes that evolved as a host defense mechanism. The discovery of decoy-receptor polymorphisms in human populations now points to an evolutionary process that allows the host to catch up with pathogens.

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