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Comment
. 2019 Feb 25;48(4):425-426.
doi: 10.1016/j.devcel.2019.02.008.

A Feedback Loop Controlling Organ Size

Allyson J Merrell  1 , Ben Z Stanger  2
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A Feedback Loop Controlling Organ Size

Allyson J Merrell et al. Dev Cell. .
Free article

Abstract

To maintain proper organ size, nature has devised trans-organ communication systems-involving both paracrine and circulating regulatory factors-to safeguard homeostasis. In this issue of Developmental Cell, Ji et al. (2019) now describe an enterohepatic feedback loop that balances tissue size and function in the mammalian liver.

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