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. 2020 Feb 18;221(5):697-700.
doi: 10.1093/infdis/jiz060.

Outbreak of Respiratory Illness Associated With Human Adenovirus Type 7 Among Persons Attending Officer Candidates School, Quantico, Virginia, 2017

Jennifer Bautista-Gogel  1 , Clifford M Madsen  1 , Xiaoyan Lu  2 , Senthilkumar K Sakthivel  2 , Irma Froh  3 , Edwin Kamau  3 , Susan I Gerber  2 , John T Watson  2 , Sarah S Cooper  1 , Eileen Schneider  2
Affiliations

Outbreak of Respiratory Illness Associated With Human Adenovirus Type 7 Among Persons Attending Officer Candidates School, Quantico, Virginia, 2017

Jennifer Bautista-Gogel et al. J Infect Dis. .

Abstract

A respiratory outbreak associated with human adenovirus type 7 (HAdV-7) occurred among unvaccinated officer candidates attending initial military training. Respiratory infections associated with HAdV-7 can be severe, resulting in significant morbidity. Genomic sequencing revealed HAdV-7d, a genome type recently remerging in the United States as a significant respiratory pathogen, following reports from Southeast Asia. Twenty-nine outbreak cases were identified; this likely represents an underestimate. Although the HAdV type 4 and 7 vaccine is currently given to US military enlisted recruit trainees, it is not routinely given to officer candidates. Administration of the HAdV type 4 and 7 vaccine may benefit this cohort.

Keywords: adenovirus; military; outbreak; respiratory; vaccine.

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