Review
Studies of development and plasticity in the olfactory sensory neuron
Affiliations
- PMID: 3078439
Item in Clipboard
Review
Studies of development and plasticity in the olfactory sensory neuron
J Physiol (Paris).
1988.
Abstract
The olfactory system is favorable for studying mechanisms of development, plasticity and regeneration. Monoclonal antibodies have been generated which differentially stain olfactory axons and can identify their earliest trajectories in the fetal rat. The developing olfactory pathway also shows differential metabolic activity, as revealed by the 2-deoxyglucose method, and these patterns show plasticity as judged by both physiological and behavioral measures. The sensory neurons undergo dieback and neurogenesis following axonal transection; electrophysiological methods are being used to reveal the membrane mechanisms underlying this unique capacity.
Similar articles
-
Onset of odorant receptor gene expression during olfactory sensory neuron regeneration.Dev Biol. 2001 Jan 1;229(1):119-27. doi: 10.1006/dbio.2000.9972. Dev Biol. 2001. PMID: 11133158
-
Neurogenesis and regeneration in the primary olfactory pathway of mammals.Bibl Anat. 1982;(23):12-25. Bibl Anat. 1982. PMID: 7138487
-
Regeneration in the peripheral and the central olfactory system: a review of morphological, physiological and behavioral aspects.J Hirnforsch. 1993;34(2):207-29. J Hirnforsch. 1993. PMID: 8228182 Review. No abstract available.
-
Long-term regeneration of abdominal vagus: efferents fail while afferents succeed.J Comp Neurol. 2003 Jan 6;455(2):222-37. doi: 10.1002/cne.10470. J Comp Neurol. 2003. PMID: 12454987
-
An olfactory bulbectomy model to study plasticity of the nervous system in rat: a review focused on published data from the Slovak Republic.Int J Neurosci. 2007 Aug;117(8):1067-90. doi: 10.1080/00207450600912271. Int J Neurosci. 2007. PMID: 17613115 Review.