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Comment
. 2019 Feb 19;50(2):273-275.
doi: 10.1016/j.immuni.2019.01.013.

Leukocyte Trafficking: Time to Take Time Seriously

Natalia Reglero-Real  1 , Loïc Rolas  2 , Sussan Nourshargh  3
Affiliations
Free article
Comment

Leukocyte Trafficking: Time to Take Time Seriously

Natalia Reglero-Real et al. Immunity. .
Free article

Abstract

Leukocyte trafficking is a key component of steady-state tissue homing and in mounting an inflammatory response. Two recent publications in Immunity by He et al. (2018) and Adrover et al. (2019) report on the diurnal regulation of these responses and the associated pathophysiological implications.

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  • Circadian Expression of Migratory Factors Establishes Lineage-Specific Signatures that Guide the Homing of Leukocyte Subsets to Tissues.
    He W, Holtkamp S, Hergenhan SM, Kraus K, de Juan A, Weber J, Bradfield P, Grenier JMP, Pelletier J, Druzd D, Chen CS, Ince LM, Bierschenk S, Pick R, Sperandio M, Aurrand-Lions M, Scheiermann C. He W, et al. Immunity. 2018 Dec 18;49(6):1175-1190.e7. doi: 10.1016/j.immuni.2018.10.007. Epub 2018 Dec 4. Immunity. 2018. PMID: 30527911 Free PMC article.
  • A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.
    Adrover JM, Del Fresno C, Crainiciuc G, Cuartero MI, Casanova-Acebes M, Weiss LA, Huerga-Encabo H, Silvestre-Roig C, Rossaint J, Cossío I, Lechuga-Vieco AV, García-Prieto J, Gómez-Parrizas M, Quintana JA, Ballesteros I, Martin-Salamanca S, Aroca-Crevillen A, Chong SZ, Evrard M, Balabanian K, López J, Bidzhekov K, Bachelerie F, Abad-Santos F, Muñoz-Calleja C, Zarbock A, Soehnlein O, Weber C, Ng LG, Lopez-Rodriguez C, Sancho D, Moro MA, Ibáñez B, Hidalgo A. Adrover JM, et al. Immunity. 2019 Feb 19;50(2):390-402.e10. doi: 10.1016/j.immuni.2019.01.002. Epub 2019 Jan 29. Immunity. 2019. PMID: 30709741

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