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Review
. 2018 Oct-Dec;14(4):289-297.
doi: 10.14797/mdcj-14-4-289.

Prediabetes: Why Should We Care?

Ashkan Zand  1 , Karim Ibrahim  1 , Bhargavi Patham  1
Affiliations
Review

Prediabetes: Why Should We Care?

Ashkan Zand et al. Methodist Debakey Cardiovasc J. 2018 Oct-Dec.

Abstract

A clear link between cardiovascular disease and prediabetes has emerged over the past few years. Recent studies have shown that patients with prediabetes can suffer from coronary artery disease and diastolic heart failure even before progressing to overt diabetes. With this knowledge, physicians must identify prediabetes and take appropriate measures to optimize glycemic control. The pathophysiological defect seen in prediabetes can be managed with lifestyle modifications; thus, it is essential that physicians have a clear understanding of the current recommendations regarding diet and exercise. This review outlines the complications associated with prediabetes, presents an overview of the available pharmacological and surgical therapies that are effective in treating it, and provides a stepwise, multipronged approach for management.

Keywords: diabetes prevention; impaired fasting glucose; impaired glucose tolerance; management of prediabetes; prediabetes.

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Conflict of interest statement

Conflict of Interest Disclosure: The authors have completed and submitted the Methodist DeBakey Cardiovascular Journal Conflict of Interest Statement and none were reported.

Figures

Figure 1.
Figure 1.
Lifestyle interventions in prediabetes; adapted from American Association of Clinical Endocrinologists guidelines.
See this image and copyright information in PMC

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