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Comment
. 2019 Feb 20;101(4):543-545.
doi: 10.1016/j.neuron.2019.01.033.

Autism in the Balance: Elevated E-I Ratio as a Homeostatic Stabilization of Synaptic Drive

Anubhuti Goel  1 , Carlos Portera-Cailliau  2
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Autism in the Balance: Elevated E-I Ratio as a Homeostatic Stabilization of Synaptic Drive

Anubhuti Goel et al. Neuron. .
Free article

Abstract

In this issue of Neuron, Antoine et al. (2019) find reduced feedforward inhibition in cortical neurons in four genetic mouse models of autism but without evidence of increased spontaneous or sensory-evoked activity.

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