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Case Reports
. 2019 Jul;23(3):E97-E99.
doi: 10.1111/hdi.12733. Epub 2019 Feb 21.

Early use of PEPA dialyzer for light chains removal and for the recovery from myeloma cast nephropathy: A case report

Gabriele Donati  1 , Fulvia Zappulo  1 , Anna Laura Croci Chiocchini  1 , Giorgia Comai  1 , Elena Zamagni  2 , Gaetano La Manna  1
Affiliations
Case Reports

Early use of PEPA dialyzer for light chains removal and for the recovery from myeloma cast nephropathy: A case report

Gabriele Donati et al. Hemodial Int. 2019 Jul.

Abstract

Chemotherapy and extracorporeal treatment reduce serum free light chains (FLCs) allowing the recovery of acute kidney injury (AKI) caused by myeloma cast nephropathy (MCN). We report the first case of recovery from AKI in a patient with MCN who underwent the removal of FLCs using the PEPA filter, with an undisclosed cut-off, combined with chemotherapy for multiple myeloma (MM).

Keywords: Bortezomib; Multiple myeloma; PEPA (Poly Ester Polymer Alloy); cast nephropathy; dialysis; free light chains.

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