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Comment
. 2019 Feb 26;3(4):599-602.
doi: 10.1182/bloodadvances.2018025155.

Platelet respiration

Andaleb Kholmukhamedov  1 , Shawn Jobe  1
Affiliations
Comment

Platelet respiration

Andaleb Kholmukhamedov et al. Blood Adv. .
No abstract available

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Conflict of interest statement

Conflict-of-interest disclosure: The authors declare no competing financial interests.

Figures

Figure 1.
Figure 1.
Summary of platelet catabolic pathways. Reactions leading to extracellular acidification caused by production of lactate and CO2 are shown with blue arrows. CoA, coenzyme A; Krebs, Krebs or tricarboxylic acid cycle; PDH, pyruvate dehydrogenase complex.
Figure 2.
Figure 2.
Glycoprotein VI–stimulated platelet respiration. Oxygen consumption (A-B,E-F) and extracellular acidification (C-D,G-H) in isolated human platelets. n ≥ 4; *P < .05 vs dimethyl sulfoxide. 2-TEDC, 2-(1-thienyl)ethyl 3,4-dihydroxybenzylidenecyanoacetate; 8,11,14-ETA, 8,11,14-eicosatriynoic acid; AA, antimycin A; ASA, acetyl salicylic acid; DMSO, dimethyl sulfoxide; OCR, oxygen consumption rate; PLT, platelet; Rot, rotenone.
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