Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Jan 17:2019:2915498.
doi: 10.1155/2019/2915498. eCollection 2019.

Corn Silk Tea for Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Shihua Shi  1 , Siming Li  2 , Weihao Li  3 , Hao Xu  2
Affiliations
Review

Corn Silk Tea for Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Shihua Shi et al. Evid Based Complement Alternat Med. .

Abstract

Corn silk, a traditional Chinese medicine, has been found to exert an antihypertensive effect in clinical practice and trials. However, systematic review of current evidence on this topic was not available. Thus, this study aims to assess safety and efficacy of corn silk tea (CST) in improving clinical outcomes in patients with hypertension. A systematic literature search was conducted through popular electronic databases up to October 2018. Randomized controlled trials (RCTs) comparing CST plus conventional antihypertensive drugs with conventional antihypertensive drugs alone were included. The main outcome was total blood pressure lowering efficacy. The risk of bias assessment according to the Cochrane Handbook was used to evaluate the methodological quality of the included trials. Review Manager 5.3 software was used for data analyses. Five RCTs involving 567 participants were included. Due to the poor quality of methodologies of most trials, limited evidence showed that CST plus antihypertensive drugs might be more effective in lowering blood pressure compared with antihypertensive drugs alone (RR = 1.27; 95% CI: 1.17 to 1.38, P<0.00001; heterogeneity: P = 0.51, I 2 = 0%, fixed-effect model). However, there is no evidence that CST plus conventional antihypertensive drugs has less adverse events than conventional antihypertensive drugs.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Figure 2
Figure 2
Figure 3
Figure 3
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Mills K. T., Bundy J. D., Kelly T. N. Global disparities of hypertension prevalence and control. Circulation. 2016;134(6):441–450. doi: 10.1161/CIRCULATIONAHA.115.018912. - DOI - PMC - PubMed
    1. Muller DC., Murphy N., Johansson M. Modifiable causes of premature death in middle-age in Western Europe: results from the EPIC cohort study. BMCl Medicine. 2016;14(1):14–87. doi: 10.1186/s12916-016-0557-y. - DOI - PMC - PubMed
    1. Kintscher U. The burden of hypertension. EuroIntervention. 2013;9:R12–R15. doi: 10.4244/EIJV9SRA3. - DOI - PubMed
    1. Pang H., Han B., Fu Q., Hao L., Zong Z. Association between homocysteine and conventional predisposing factors on risk of stroke in patients with hypertension. Scientific Reports. 2018;8(1):p. 3900. doi: 10.1038/s41598-018-22260-6. - DOI - PMC - PubMed
    1. Poulter N. R., Prabhakaran D., Caulfield M. Hypertension. The Lancet. 2015;386(9995):801–812. doi: 10.1016/S0140-6736(14)61468-9. - DOI - PubMed

LinkOut - more resources