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. 2019 Feb 22;14(2):e0211680.
doi: 10.1371/journal.pone.0211680. eCollection 2019.

Spontaneous ilio-psoas hematomas complicating intensive care unit hospitalizations

Thierry Artzner  1 , Raphaël Clere-Jehl  1   2 , Malika Schenck  3 , Michel Greget  4 , Hamid Merdji  1   5 , Pierre De Marini  4 , Nicolas Tuzin  6   7 , Julie Helms  1   2 , Ferhat Meziani  1   5
Affiliations

Spontaneous ilio-psoas hematomas complicating intensive care unit hospitalizations

Thierry Artzner et al. PLoS One. .

Abstract

Background: Ilio-psoas hematoma is a potentially lethal condition that can arise during hospital stay. However, neither the incidence nor the prognosis of patients whose stay in intensive care units (ICU) is complicated by a iatrogenic ilio-psoas hematoma is known.

Methods: A bicentric retrospective study was conducted to compile the patients who developed an ilio-psoas hematoma while they were hospitalized in ICU between January 2009 and December 2016. Their biometric characteristics, pre-existing conditions, the circumstances in which the hematoma was diagnosed, the treatments they received and their prognosis were recorded.

Results: Forty patients were diagnosed with an ilio-psoas hematoma during their ICU stay. The incidence of this complication was 3.8 cases for 1000 admissions, taking into account only patients who stayed more than three days in ICU. The median age of patients was 74 years old and the median time between admission and the diagnosis of ilio-psoas hematoma was 12.6 days. A large proportion of them was obese (42.5%) and/or under dialysis (50%) prior to developing their hematoma. Ninety-five percent of the patients had heparin at prophylactic or therapeutic doses. Only 10% of them were above the therapeutic range of anticoagulation. The ICU mortality rate was of 50% following this complication (versus a general mortality rate of 22% for the patients without IPH over the same period of time). Patients with IPH that were complicated by disseminated intravascular coagulopathy had a significantly higher mortality rate than those with IPH and no disseminated intravascular coagulopathy (OR 6.91, 95% CI [1.28; 58.8], p = 0.04).

Conclusion: Age, anticoagulation, a high body mass index and dialysis seem to be risk factors of developing an ilio-psoas hematoma in ICU. Iatrogenic ilio-psoas hematomas complicated by disseminated intravascular coagulopathies are more at risk of leading to death. It is noteworthy that activated partial thromboplastin time above the therapeutic range was not a good predictor of developing a hematoma for patients who received unfractioned heparin therapy.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Study flowchart.
Fig 2
Fig 2. Spontaneous left psoas hematoma in a 70-year-old patient.
(A) Axial CT scan of the abdomen without contrast shows swelling of the left psoas with retroperitoneal diffusion (B) Axial contrast-enhanced CT scan shows extravasation of contrast medium (arrow).
See this image and copyright information in PMC

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