Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Jun;98(6):655-62.
doi: 10.1111/j.1365-2133.1978.tb03584.x.

Relationship between T and B lymphocyte values and prognosis in malignant melanoma

M G Bernengo, G Capella, M Peruccio, G Zina

Relationship between T and B lymphocyte values and prognosis in malignant melanoma

M G Bernengo et al. Br J Dermatol. 1978 Jun.

Abstract

T and B lymphocyte populations were evaluated in 56 patients with malignant melanoma. Active rosettes (T-Ea) were decreased only in metastatic patients, while the total T population (T-Et) was decreased in all stages. In addition the metastatic patients presented significant decreases in IgD and IgM subpopulations. An increase in null cells was noted in metastatic patients. Regular controls over a period of 2 years showed that T-Ea levels were closely linked to the clinical picture. Patients whose values were constant remained cancer free, while a reduction heralded the appearance of clinical and/or radiological signs of metastasis.

PubMed Disclaimer

Substances