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Editorial
. 2019 May;58(5):478-480.
doi: 10.1016/j.jaac.2018.09.426. Epub 2019 Feb 22.

Editorial: Pharmacological Effects on Striatal Resting-State Connectivity in Pediatric Obsessive-Compulsive Disorder: An Opportunity to Modulate Neurodevelopmental Trajectories?

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Editorial

Editorial: Pharmacological Effects on Striatal Resting-State Connectivity in Pediatric Obsessive-Compulsive Disorder: An Opportunity to Modulate Neurodevelopmental Trajectories?

Esther Via. J Am Acad Child Adolesc Psychiatry. 2019 May.

Abstract

The cortico-striato-thalamo-cortical (CSTC) circuit has been traditionally implicated in the underlying neural pathophysiology of obsessive-compulsive disorder (OCD). The CSTC involves parallel, partly segregated, but intrinsically communicating circuits involved in motor, cognitive, affective, and motivational processes.1,2.

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