Editorial: Pharmacological Effects on Striatal Resting-State Connectivity in Pediatric Obsessive-Compulsive Disorder: An Opportunity to Modulate Neurodevelopmental Trajectories?
- PMID: 30799068
- DOI: 10.1016/j.jaac.2018.09.426
Editorial: Pharmacological Effects on Striatal Resting-State Connectivity in Pediatric Obsessive-Compulsive Disorder: An Opportunity to Modulate Neurodevelopmental Trajectories?
Abstract
The cortico-striato-thalamo-cortical (CSTC) circuit has been traditionally implicated in the underlying neural pathophysiology of obsessive-compulsive disorder (OCD). The CSTC involves parallel, partly segregated, but intrinsically communicating circuits involved in motor, cognitive, affective, and motivational processes.1,2.
Copyright © 2018 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.
Comment on
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Sertraline Effects on Striatal Resting-State Functional Connectivity in Youth With Obsessive-Compulsive Disorder: A Pilot Study.J Am Acad Child Adolesc Psychiatry. 2019 May;58(5):486-495. doi: 10.1016/j.jaac.2018.07.897. Epub 2018 Oct 30. J Am Acad Child Adolesc Psychiatry. 2019. PMID: 30768407 Free PMC article. Clinical Trial.
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