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Case Reports
. 2019 Feb 19;2019(2):rjz046.
doi: 10.1093/jscr/rjz046. eCollection 2019 Feb.

Schwannoma in the ascending colon, a rare finding on surveillance colonoscopy

Mirza M A S Baig  1 , Rikesh Patel  2 , Mohamad Ali Kazem  3 , Arif Khan  3
Affiliations
Case Reports

Schwannoma in the ascending colon, a rare finding on surveillance colonoscopy

Mirza M A S Baig et al. J Surg Case Rep. .

Abstract

Schwannomas are peripheral nerve sheath tumours that can present as a rare tumour of GI tract, and even more uncommonly within the colon. We present a case of colonic schwannoma in an asymptomatic patient identified on surveillance colonoscopy. The tumour is of mesenchymal origin and is often challenging to diagnose prior to surgical resection. Endoscopy usually fails to provide adequate sample and diagnosis is usually confirmed on immunohistochemistry.

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Figures

Figure 1:
Figure 1:
Colonoscopy image of the ascending colon showing submucosal lesion.
Figure 2:
Figure 2:
Colonoscopy image of the ascending colon showing submucosal lesion.
Figure 3:
Figure 3:
12 mm polypoidal mass (white arrow) visible on axial image of post-contrast CTVC.
Figure 4:
Figure 4:
12 mm polypoidal mass (white arrow) visible on coronal image of post-contrast CTVC.
Figure 5:
Figure 5:
12 mm polypoidal mass (white arrow) visible on sagittal image of post-contrast CTVC.
Figure 6:
Figure 6:
H&E staining showing submucosal tumour with spindle cells and verocay bodies.
Figure 7:
Figure 7:
Immunohistochemical staining- strongly positive for S100.
See this image and copyright information in PMC

References

    1. de Mesquita Neto JW, Lima Verde Leal RM, de Brito EV, Cordeiro DF, Costa ML. Solitary schwannoma of the cecum: case report and review of the literature. Case Rep Oncol 2013;6:62–5. - PMC - PubMed
    1. Bohlok A, El Khoury M, Bormans A, Galdon MG, Vouche M, El Nakadi I, et al. . Schwannoma of the colon and rectum: a systematic literature review. World J Surg Oncol 2018;16:125 doi:10.1186/s12957-018-1427-1. - DOI - PMC - PubMed
    1. Hou YY, Tan YS, Xu JF, Wang XN, Lu SH, Ji Y, et al. . Schwannoma of the gastrointestinal tract: a clinicopathological, immunohistochemical and ultrastructural study of 33 cases. Histopathology 2006;48:536–45. doi:10.1111/j.1365-2559.2006.02370.x. - DOI - PubMed
    1. Dickson-Lowe RA, James CL, Bailey CM, Abdulaal Y. Caecal schwannoma: a rare cause of per rectal bleeding in a 72-year-old man. BMJ Case Rep 2014;10.1136/bcr-2014-205643. - DOI - PMC - PubMed
    1. Tsunoda C, Kato H, Sakamoto T, Yamada R, Mitsumaru A, Yokomizo H, et al. . A case of benign schwannoma of the transverse colon with granulation tissue. Case Rep Gastroenterol 2009;3:116–20. 10.1159/000214837. - DOI - PMC - PubMed

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