Specific pathogen-free (SPF) animal status as a variable in biomedical research: Have we come full circle?

Affiliations

¹ Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, Queensland 4811, Australia. Electronic address: geoffrey.dobson@jcu.edu.au.
² Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, Queensland 4811, Australia. Electronic address: hayley.letson@jcu.edu.au.
³ Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, Queensland 4811, Australia. Electronic address: erik.biros@jcu.edu.au.
⁴ Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, Queensland 4811, Australia; The Orthopaedic Research Institute of Queensland (ORIQL), Townsville, Queensland 4812, Australia. Electronic address: jodie.morris1@jcu.edu.au.

Geoffrey P Dobson et al. EBioMedicine. 2019 Mar.

. 2019 Mar:41:42-43.

doi: 10.1016/j.ebiom.2019.02.038. Epub 2019 Feb 23.

¹ Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, Queensland 4811, Australia. Electronic address: geoffrey.dobson@jcu.edu.au.
² Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, Queensland 4811, Australia. Electronic address: hayley.letson@jcu.edu.au.
³ Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, Queensland 4811, Australia. Electronic address: erik.biros@jcu.edu.au.
⁴ Heart, Trauma and Sepsis Research Laboratory, College of Medicine and Dentistry, James Cook University, Queensland 4811, Australia; The Orthopaedic Research Institute of Queensland (ORIQL), Townsville, Queensland 4812, Australia. Electronic address: jodie.morris1@jcu.edu.au.

No abstract available

Keywords: Biomedical research; Clinical trial; Gut; Microbiome; Reproducibility; Rodent; Specific pathogen free; Translation.

References

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