Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Feb 5:10:58.
doi: 10.3389/fneur.2019.00058. eCollection 2019.

A Systemic Review of Functional Near-Infrared Spectroscopy for Stroke: Current Application and Future Directions

Muyue Yang  1   2 , Zhen Yang  3 , Tifei Yuan  4 , Wuwei Feng  5 , Pu Wang  1
Affiliations

A Systemic Review of Functional Near-Infrared Spectroscopy for Stroke: Current Application and Future Directions

Muyue Yang et al. Front Neurol. .

Abstract

Background: Survivors of stroke often experience significant disability and impaired quality of life. The recovery of motor or cognitive function requires long periods. Neuroimaging could measure changes in the brain and monitor recovery process in order to offer timely treatment and assess the effects of therapy. A non-invasive neuroimaging technique near-infrared spectroscopy (NIRS) with its ambulatory, portable, low-cost nature without fixation of subjects has attracted extensive attention. Methods: We conducted a comprehensive literature review in order to review the use of NIRS in stroke or post-stroke patients in July 2018. NCBI Pubmed database, EMBASE database, Cochrane Library and ScienceDirect database were searched. Results: Overall, we reviewed 66 papers. NIRS has a wide range of application, including in monitoring upper limb, lower limb recovery, motor learning, cortical function recovery, cerebral hemodynamic changes, cerebral oxygenation, as well as in therapeutic method, clinical researches, and evaluation of the risk for stroke. Conclusions: This study provides a preliminary evidence of the application of NIRS in stroke patients as a monitoring, therapeutic, and research tool. Further studies could give more emphasize on the combination of NIRS with other techniques and its utility in the prevention of stroke.

Keywords: cortical function; motor recovery; near-infrared spectroscopy; stroke; systemic review.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Flowchart of literature search.
Figure 2
Figure 2
Summary of the application of NIRS.
See this image and copyright information in PMC

References

    1. Donnan GA, Fisher M, Macleod M, Davis SM. Stroke. Lancet (2008) 371:1612–23. 10.1016/S0140-6736(08)60694-7 - DOI - PubMed
    1. Feigin V, Roth G, Naghavi M, Parmar P, Krishnamurthi R, Chugh S, et al. Global burden of stroke and risk factors in 188 countries, during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet Neurol. (2016) 15:913–24. 10.1016/S1474-4422(16)30073-4 - DOI - PubMed
    1. Schweizer TA, Schweizer TA, Fachgebiete H. The behavioral consequences of stroke (2013).
    1. Handley A, Medcalf P, Hellier K, Dutta D. Movement disorders after stroke. Age Ageing (2009) 38:260–66. 10.1093/ageing/afp020 - DOI - PubMed
    1. Elias G, Namasivayam AA, Lozano AM. Deep brain stimulation for stroke: current uses and future directions. Brain Stimulat. (2017) 11:3–28. 10.1016/j.brs.2017.10.005 - DOI - PubMed

LinkOut - more resources