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Review
. 2015 Jun;2(2):47-58.
doi: 10.1016/j.ijpam.2015.05.006. Epub 2015 Jun 19.

The road for survival improvement of cystic fibrosis patients in Arab countries

Hanaa Banjar  1 , Gerhild Angyalosi  2
Affiliations
Review

The road for survival improvement of cystic fibrosis patients in Arab countries

Hanaa Banjar et al. Int J Pediatr Adolesc Med. 2015 Jun.

Abstract

Cystic fibrosis (CF) is a lethal, monogenic disorder that affects multiple organ systems of the body. The incidence has been described before in the Middle East to be 1 in 2000 to 1 in 5800 live births, and the median survival was estimated to be from 10 to 20 years of age. The present article attempts to revisit various facets of this disease and specifically highlights the most important lacunae that exist in treating CF. In addition, it also tries to emphasize the steps in improving the median survival of patients with CF, in these countries.

Keywords: CF, cystic fibrosis; CFRD, cystic fibrosis related diabetes; CFTR; CFTR, cystic fibrosis transmembrane conductance regulator; Cystic fibrosis; FEV1, forced expiratory volume in 1 second; Middle East; P. aeruginosa; P. aeruginosa, Pseudomonas aeruginosa; Survival; Treatment.

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Figures

Figure 1
Figure 1
Overview of types of functional mutations in CFTR.
Figure 2
Figure 2
Comparison of normal vs defective epithelial fluid secretion in patients with cystic fibrosis.
See this image and copyright information in PMC

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