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. 2018 Mar;5(1):13-17.
doi: 10.1016/j.ijpam.2018.01.001. Epub 2018 Feb 24.

Etiology and clinical characteristics of pediatric acute pancreatitis in Saudi Arabia: a 20-year experience from a single tertiary center

Abdulrahman Alabdulkareem  1 , Tameem Almahmoud  1 , Husam Al-Tahan  1 , Sundas Javad  2 , Maher Al Hatlani  3
Affiliations

Etiology and clinical characteristics of pediatric acute pancreatitis in Saudi Arabia: a 20-year experience from a single tertiary center

Abdulrahman Alabdulkareem et al. Int J Pediatr Adolesc Med. 2018 Mar.

Abstract

Background: Cases of acute pancreatitis (AP) have increased among pediatric populations worldwide; however, the natural course of this condition in Saudi Arabia was unknown.

Aim: To report the characteristics as well as outcomes of pediatric AP.

Patients and methods: A retrospective chart review study was conducted to include acute pancreatitis in patients ≤ 19 years. The period was from 1994 until 2015. Demographic, clinical, laboratory, imaging and outcome data were collected and analyzed.

Results: 50 patients (n = 26; 52% males vs. n = 24; 48% females) were included. The mean age at diagnosis was 11.6 years. The mean length of hospital stay was 10.5 days. 9 (18%) patients had a recurrence of AP and 4 (8%) had complications. Idiopathic AP was the most frequent etiology (n = 21; 42%), followed by cholelithiasis (n = 11; 22%). 2 patients (4%) had drug-induced AP, where one was taking isoniazid and the other had taken a large amount of erythromycin, amoxicillin and ibuprofen. 2 choledochal cysts complicated by AP (4%). Pancreaticobiliary diseases, as a complete entity, accounted for 34% (n = 17). Clinically, abdominal pain (n = 47; 94%) and vomiting (n = 38; 76%) were most commonly encountered. KUB was non-diagnostic in all patients. No patient died during their admission.

Conclusion: Although still relatively uncommon in Saudi Arabia, there are on average 2-3 cases of pediatric AP diagnosed annually in our institution. Idiopathic AP was the most common cause. Isoniazid and choledochal cysts are rare causes of AP and were reported in the study.

Keywords: Choledochal cyst; Gastroenterology; Isoniazid; Pancreatitis; Pediatric; Saudi Arabia.

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References

    1. Bai H.X., Lowe M.E., Husain S.Z. What have we learned about acute pancreatitis in children? J Pediatr Gastroenterol Nutr. 2011;52(3):262–270. - PMC - PubMed
    1. Banks P.A., Bollen T.L., Dervenis C., Gooszen H.G., Johnson C.D., Sarr M.G. Classification of acute pancreatitis –2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2012;62(1):102–111. - PubMed
    1. Morinville V.D., Husain S.Z., Bai H., Barth B., Alhosh R., Durie P.R. Definitions of pediatric pancreatitis and survey of present clinical practices. J Pediatr Gastroenterol Nutr. 2012 Sep;55(3):261–265. - PMC - PubMed
    1. Yadav D., Lowenfels A.B. The epidemiology of pancreatitis and pancreatic cancer. Gastroenterology. 2013;144(6):1252–1261. - PMC - PubMed
    1. Pant C., Deshpande A., Olyaee M., Anderson M.P., Bitar A., Steele M.I. Epidemiology of acute pancreatitis in hospitalized children in the United States from 2000–2009. PLoS One. 2014 May 7;9(5) - PMC - PubMed