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Clinical Trial
. 2020 Jan;46(1):78-85.
doi: 10.1097/DSS.0000000000001869.

Jowl Reduction With Deoxycholic Acid

José Raúl Montes  1 , Elizabeth Santos  1 , Annirudha Chillar  2
Affiliations
Clinical Trial

Jowl Reduction With Deoxycholic Acid

José Raúl Montes et al. Dermatol Surg. 2020 Jan.

Abstract

Background: The study proposes a novel protocol for targeting the jowls using deoxycholic acid (DCA) injections, with emphasis on safety and feasibility of the procedure.

Methods: This prospective study was conducted at a cosmetic practice between June 2016 and May 2017. Twelve consecutive patients seeking reduction/improvement in mild/moderate jowl fat were injected with DCA subcutaneously in a predefined circular area 1.0 cm above the mandibular border. Treatment response was assessed using physician-evaluated Global Aesthetic Improvement Scale (GAIS) and Subject GAIS.

Results: Twelve patients (11 women and 1 man) with mild (n = 8) or moderate (n = 4) jowls were treated. After the first treatment, GAIS responses for 24 jowls showed 5 jowls with vast improvement, 15 with moderate improvement, and 4 with no change. After the second session for 5 jowls in 3 patients, GAIS responses showed vast improvement in 4 jowls and moderate improvement in 1. Adverse events included induration (n = 4), bruising (n = 6), numbness (n = 2), pain (n = 5), redness (n = 3), edema (n = 9), and dysphagia (n = 1).

Conclusion: Results of this early experience showed that DCA injections were safe and effective for nonsurgical jowl reduction.

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References

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