Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2019 Mar 1;142(3):498-501.
doi: 10.1093/brain/awz014.

REM sleep behaviour disorder: an early window for prevention in neurodegeneration?

Affiliations
Comment

REM sleep behaviour disorder: an early window for prevention in neurodegeneration?

Rimona S Weil et al. Brain. .

Abstract

This scientific commentary refers to ‘Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study’ by Postuma et al. (doi:10.1093/brain/awz030).

PubMed Disclaimer

Comment on

  • Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study.
    Postuma RB, Iranzo A, Hu M, Högl B, Boeve BF, Manni R, Oertel WH, Arnulf I, Ferini-Strambi L, Puligheddu M, Antelmi E, Cochen De Cock V, Arnaldi D, Mollenhauer B, Videnovic A, Sonka K, Jung KY, Kunz D, Dauvilliers Y, Provini F, Lewis SJ, Buskova J, Pavlova M, Heidbreder A, Montplaisir JY, Santamaria J, Barber TR, Stefani A, St Louis EK, Terzaghi M, Janzen A, Leu-Semenescu S, Plazzi G, Nobili F, Sixel-Doering F, Dusek P, Bes F, Cortelli P, Ehgoetz Martens K, Gagnon JF, Gaig C, Zucconi M, Trenkwalder C, Gan-Or Z, Lo C, Rolinski M, Mahlknecht P, Holzknecht E, Boeve AR, Teigen LN, Toscano G, Mayer G, Morbelli S, Dawson B, Pelletier A. Postuma RB, et al. Brain. 2019 Mar 1;142(3):744-759. doi: 10.1093/brain/awz030. Brain. 2019. PMID: 30789229 Free PMC article. Clinical Trial.

References

    1. Athauda D, Maclagan K, Skene SS, Bajawa-joseph M, Letchfors D, Chowdhury K, et al.Exenatide once weekly versus placebo in Parkinson’s disease: a randomised, double-blind, placebo-controlled trial. Lancet 2017; 390: 1664–75. - PMC - PubMed
    1. Darweesh SKL, Wolters FJ, Postuma RB, Stricker BH, Hofman A, Koudstaal PJ, et al.Association between poor cognitive functioning and risk of incident parkinsonism. JAMA Neurol 2017; 74: 1431. - PMC - PubMed
    1. Iranzo A, Tolosa E, Gelpi E, Molinuevo JL, Valldeoriola F, Serradell M, et al.Neurodegenerative disease status and post-mortem pathology in idiopathic rapid-eye-movement sleep behaviour disorder: an observational cohort study. Lancet Neurol 2013; 12: 443–53. - PubMed
    1. Khera AV, Chaffin M, Aragam KG, Haas ME, Roselli C, Choi SH, et al.Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. Nat Genet 2018; 50: 1219–24. - PMC - PubMed
    1. Morrison PJ, Harding-Lester S, Bradley A. Uptake of Huntington disease predictive testing in a complete population. Clin Genet 2011; 80: 281–6. - PubMed

Publication types