Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Feb 22;5(1):9.
doi: 10.3390/gels5010009.

Protein-Based Nanostructures for Food Applications

Affiliations
Review

Protein-Based Nanostructures for Food Applications

Ana I Bourbon et al. Gels. .

Abstract

Proteins are receiving significant attention for the production of structures for the encapsulation of active compounds, aimed at their use in food products. Proteins are one of the most used biomaterials in the food industry due to their nutritional value, non-toxicity, biodegradability, and ability to create new textures, in particular, their ability to form gel particles that can go from macro- to nanoscale. This review points out the different techniques to obtain protein-based nanostructures and their use to encapsulate and release bioactive compounds, while also presenting some examples of food grade proteins, the mechanism of formation of the nanostructures, and the behavior under different conditions, such as in the gastrointestinal tract.

Keywords: bio-based materials; biopolymers; encapsulation; nanohydrogel; nanotechnology.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Lactoferrin particles at the submicron scale produced by a nanospraydrier. The image was obtained by scanning electron microscopy.
Figure 2
Figure 2
Lactoferrin particles at the submicron scale produced by electrospray. The image was obtained by scanning electron microscopy.

References

    1. Hamidi M., Azadi A., Rafiei P. Hydrogel nanoparticles in drug delivery. Adv. Drug Deliv. Rev. 2008;60:1638–1649. doi: 10.1016/j.addr.2008.08.002. - DOI - PubMed
    1. Daniel-da-Silva A.L., Ferreira L., Gil A.M., Trindade T. Synthesis and swelling behavior of temperature responsive κ-carrageenan nanogels. J. Colloid Interface Sci. 2011;355:512–517. doi: 10.1016/j.jcis.2010.12.071. - DOI - PubMed
    1. Belščak-Cvitanović A., Komes D., Karlović S., Djaković S., Spoljarić I., Mršić G., Ježek D. Improving the controlled delivery formulations of caffeine in alginate hydrogel beads combined with pectin, carrageenan, chitosan and psyllium. Food Chem. 2015;167:378–386. doi: 10.1016/j.foodchem.2014.07.011. - DOI - PubMed
    1. Hong Y.-H., McClements D.J. Formation of Hydrogel Particles by Thermal Treatment of β-Lactoglobulin−Chitosan Complexes. J. Agric. Food Chem. 2007;55:5653–5660. doi: 10.1021/jf070564n. - DOI - PubMed
    1. Abaee A., Mohammadian M., Jafari S.M. Whey and soy protein-based hydrogels and nano-hydrogels as bioactive delivery systems. Trends Food Sci. Technol. 2017;70:69–81. doi: 10.1016/j.tifs.2017.10.011. - DOI

LinkOut - more resources