Clinical Trial
[The effect of bencyclane, flunarizine and naftidrofuryl on a calorically induced long time nystagmus (author's transl)]
[Article in
German]
- PMID: 308146
Item in Clipboard
Clinical Trial
[The effect of bencyclane, flunarizine and naftidrofuryl on a calorically induced long time nystagmus (author's transl)]
[Article in
German]
Laryngol Rhinol Otol (Stuttg).
1978 Aug.
Abstract
The method of a calorically induced long time stimulation is shown. Appr. 15 minutes after begin fo stimulation a nystagmus plateau can be observed. We used this plateau to demonstrate the effects of three cerebral vasoactive drugs--Bencyclane, Flunarizine and Naftidrofuryl-Hydrogenoxalate in a randomized double blind study. All of them depressed the nystagmus significantly. Naftidrofuryl by 38.4 +/- 4.6%, Flunarizine by 31 +/- 4.5% and Bencyclane by 25.1 +/- 3.8%. The depressing mechanism of Flunarizine is partly due to sedation.
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