Rational Design of Gene Therapy Vectors

doi:10.1016/j.omtm.2019.01.009

Editorial

. 2019 Feb 16:12:246-247.

doi: 10.1016/j.omtm.2019.01.009. eCollection 2019 Mar 15.

Rational Design of Gene Therapy Vectors

Dao Pan^{1

2}, Hildegard Büning^{3

4}, Chen Ling^{5

6}

Affiliations

¹ Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
² Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA.
³ Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany.
⁴ REBIRTH Cluster of Excellence, Hannover Medical School, Hannover, Germany.
⁵ Division of Cellular and Molecular Therapy, Department of Pediatrics, University of Florida, Gainesville, FL, USA.
⁶ State Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai, China.

PMID: 30815510
PMCID: PMC6378344
DOI: 10.1016/j.omtm.2019.01.009

Editorial

Rational Design of Gene Therapy Vectors

Dao Pan et al. Mol Ther Methods Clin Dev. 2019.

. 2019 Feb 16:12:246-247.

doi: 10.1016/j.omtm.2019.01.009. eCollection 2019 Mar 15.

Authors

Dao Pan^{1

2}, Hildegard Büning^{3

4}, Chen Ling^{5

6}

Affiliations

¹ Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
² Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA.
³ Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany.
⁴ REBIRTH Cluster of Excellence, Hannover Medical School, Hannover, Germany.
⁵ Division of Cellular and Molecular Therapy, Department of Pediatrics, University of Florida, Gainesville, FL, USA.
⁶ State Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai, China.

PMID: 30815510
PMCID: PMC6378344
DOI: 10.1016/j.omtm.2019.01.009

No abstract available

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References

1. Dunbar C.E., High K.A., Joung J.K., Kohn D.B., Ozawa K., Sadelain M. Gene therapy comes of age. Science. 2018;359:359. - PubMed
1. Frank A.M., Buchholz C.J. Surface-Engineered Lentiviral Vectors for Selective Gene Transfer into Subtypes of Lymphocytes. Mol. Ther. Methods Clin. Dev. 2018;12:19–31. - PMC - PubMed
1. Merlin S., Follenzi A. Transcriptional targeting and microRNA regulation of lentiviral vectors. Mol. Ther. Methods Clin. Dev. 2019 Published online January 8, 2019. - PMC - PubMed
1. Büning H., Srivastava A. Capsid modifications for targeting and improving the efficacy of AAV vectors. Mol. Ther. Methods Clin. Dev. 2019 - PMC - PubMed
1. Davis R., Gurumurthy A., Hossain M.A., Gunn E.M., Bungert J. Engineering Globin Gene Expression. Mol. Ther. Methods Clin. Dev. 2018;12:102–110. - PMC - PubMed

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[1] Dunbar C.E., High K.A., Joung J.K., Kohn D.B., Ozawa K., Sadelain M. Gene therapy comes of age. Science. 2018;359:359. - PubMed

[2] Dunbar C.E., High K.A., Joung J.K., Kohn D.B., Ozawa K., Sadelain M. Gene therapy comes of age. Science. 2018;359:359. - PubMed

[3] Frank A.M., Buchholz C.J. Surface-Engineered Lentiviral Vectors for Selective Gene Transfer into Subtypes of Lymphocytes. Mol. Ther. Methods Clin. Dev. 2018;12:19–31. - PMC - PubMed

[4] Frank A.M., Buchholz C.J. Surface-Engineered Lentiviral Vectors for Selective Gene Transfer into Subtypes of Lymphocytes. Mol. Ther. Methods Clin. Dev. 2018;12:19–31. - PMC - PubMed

[5] Merlin S., Follenzi A. Transcriptional targeting and microRNA regulation of lentiviral vectors. Mol. Ther. Methods Clin. Dev. 2019 Published online January 8, 2019. - PMC - PubMed

[6] Merlin S., Follenzi A. Transcriptional targeting and microRNA regulation of lentiviral vectors. Mol. Ther. Methods Clin. Dev. 2019 Published online January 8, 2019. - PMC - PubMed

[7] Büning H., Srivastava A. Capsid modifications for targeting and improving the efficacy of AAV vectors. Mol. Ther. Methods Clin. Dev. 2019 - PMC - PubMed

[8] Büning H., Srivastava A. Capsid modifications for targeting and improving the efficacy of AAV vectors. Mol. Ther. Methods Clin. Dev. 2019 - PMC - PubMed

[9] Davis R., Gurumurthy A., Hossain M.A., Gunn E.M., Bungert J. Engineering Globin Gene Expression. Mol. Ther. Methods Clin. Dev. 2018;12:102–110. - PMC - PubMed

[10] Davis R., Gurumurthy A., Hossain M.A., Gunn E.M., Bungert J. Engineering Globin Gene Expression. Mol. Ther. Methods Clin. Dev. 2018;12:102–110. - PMC - PubMed

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Rational Design of Gene Therapy Vectors

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Rational Design of Gene Therapy Vectors

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