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. 2019;23(3):232-238.
doi: 10.1007/s12603-019-1170-5.

Association of Handgrip Strength and Muscle Mass with Dependency in (Instrumental) Activities of Daily Living in Hospitalized Older Adults -The EMPOWER Study

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Association of Handgrip Strength and Muscle Mass with Dependency in (Instrumental) Activities of Daily Living in Hospitalized Older Adults -The EMPOWER Study

C G M Meskers et al. J Nutr Health Aging. 2019.

Abstract

Objectives: Handgrip strength (HGS) and muscle mass are strong predictors for dependency in Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) in community dwelling older adults. Whether this also applies to older hospitalized patients is yet unknown. We studied the association between HGS and muscle mass with ADL and IADL dependency at admission and change of ADL and IADL dependency at three months after discharge in older hospitalized patients.

Design: Observational longitudinal inception cohort (EMPOWER) including 378 patients aged 70 years and older.

Setting: Four different clinical wards of a university teaching hospital, The Netherlands.

Measurements: HGS and muscle mass were measured within 48 hours after admission using hand dynamometry and Bio-electrical Impedance Analysis respectively. ADL dependency was assessed using the Katz score (0-6 points) and IADL dependency using the Lawton and Brody score (0-8 points) within 48 hours after admission and three months after discharge.

Results: At admission, lower HGS was associated with ADL dependency in both males and females. Lower muscle mass was associated with ADL dependency in males. Lower HGS was associated with IADL dependency, but only in males. Lower HGS at admission in males was associated with an increase in ADL dependency three months after discharge.

Conclusion: In hospitalized older patients, HGS is associated with ADL and IADL and muscle mass measures with ADL in male patients only. HGS should be explored as predictive marker for outcome of hospitalized older patients after discharge.

Keywords: Muscles; activities of daily living; aged; handgrip strength; hospitalization; muscle mass; muscle strength; outcome assessment.

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Conflict of interest statement

None of the authors report a conflict of interest

References

    1. Reed RL, Isherwood L, Ben-Tovim D. Why do older people with multi-morbidity experience unplanned hospital admissions from the community: a root cause analysis. BMC Health Serv Res. 2015;15:525. 10.1186/s12913-015-1170-z - DOI - PMC - PubMed
    1. Ehlenbach WJ, Hough CL, Crane PK, Haneuse SJ, Carson SS, Curtis JR, et al. Association between acute care and critical illness hospitalization and cognitive function in older adults. JAMA. 2010;303(8):763–770. 10.1001/jama.2010.167 PubMed PMID: 20179286, PMCID 2943865. - DOI - PMC - PubMed
    1. Covinsky KE, Palmer RM, Fortinsky RH, Counsell SR, Stewart AL, Kresevic D, et al. Loss of independence in activities of daily living in older adults hospitalized with medical illnesses: increased vulnerability with age. J Am Geriatr Soc. 2003;51(4):451–458. 10.1046/j.1532-5415.2003.51152.x PubMed PMID: 12657063. - DOI - PubMed
    1. Sager MA, Franke T, Inouye SK, Landefeld CS, Morgan TM, Rudberg MA, et al. Functional outcomes of acute medical illness and hospitalization in older persons. Arch Intern Med. 1996;156(6):645–652. 10.1001/archinte.1996.00440060067008 PubMed PMID: 8629876. - DOI - PubMed
    1. Creditor MC. Hazards of hospitalization of the elderly. Ann Intern Med. 1993;118(3):219–223. 10.7326/0003-4819-118-3-199302010-00011 PubMed PMID: 8417639. - DOI - PubMed

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