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Review
. 2019 Jun;105(6):1285-1296.
doi: 10.1002/JLB.MR0718-298R. Epub 2019 Mar 1.

Microbial killing by NK cells

Christopher H Mody  1   2   3 , Henry Ogbomo  1   2 , Richard F Xiang  1   2 , Stephen K Kyei  1   2 , David Feehan  1   2 , Anowara Islam  1   2 , Shu Shun Li  1   2
Affiliations
Review

Microbial killing by NK cells

Christopher H Mody et al. J Leukoc Biol. 2019 Jun.

Abstract

It is now evident that NK cells kill bacteria, fungi, and parasites in addition to tumor and virus-infected cells. In addition to a number of recent publications that have identified the receptors and ligands, and mechanisms of cytotoxicity, new insights are reflected in the reports from researchers all over the world at the 17th Meeting of the Society for Natural Immunity held in San Antonio, TX, USA from May 28 through June 1, 2018. We will provide an overview of the field and discuss how the presentations at the meeting might shape our knowledge and future directions in the field.

Keywords: NK activating receptors; NK cells; granule trafficking; microbial killing; signal transduction.

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