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Comment
. 2019 Apr;9(4):OF6.
doi: 10.1158/2159-8290.CD-NB2019-029. Epub 2019 Mar 1.

Darolutamide Slows Metastasis in Prostate Cancer

No authors listed
Comment

Darolutamide Slows Metastasis in Prostate Cancer

No authors listed. Cancer Discov. 2019 Apr.

Abstract

The phase III ARAMIS study shows that the androgen-receptor antagonist darolutamide delays metastasis in men with castration-resistant prostate cancer by a median of 22 months compared with a placebo. Researchers also found that side effects associated with other drugs in this class were no more common in the placebo group than the darolutamide group.

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  • Darolutamide in Nonmetastatic, Castration-Resistant Prostate Cancer.
    Fizazi K, Shore N, Tammela TL, Ulys A, Vjaters E, Polyakov S, Jievaltas M, Luz M, Alekseev B, Kuss I, Kappeler C, Snapir A, Sarapohja T, Smith MR; ARAMIS Investigators. Fizazi K, et al. N Engl J Med. 2019 Mar 28;380(13):1235-1246. doi: 10.1056/NEJMoa1815671. Epub 2019 Feb 14. N Engl J Med. 2019. PMID: 30763142 Clinical Trial.

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