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Comparative Study
. 1986:14 Suppl 1:S26-30.
doi: 10.1007/BF01645194.

[Dependence of the bactericidal activity and mutant selection of 4-quinolones on their serum concentration levels]

[Article in German]
A Bauernfeind, C Petermüller, B Heinrich, R Gablac
Comparative Study

[Dependence of the bactericidal activity and mutant selection of 4-quinolones on their serum concentration levels]

[Article in German]
A Bauernfeind et al. Infection. 1986.

Abstract

In an in vitro system, bacterial cultures were exposed to concentrations following the kinetics of 4-quinolones in human serum. Both killing kinetics of staphylococci and enterococci and selection of resistant mutants were shown to be influenced by the pharmacokinetik parameters of the individual substances.

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References

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