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Review
. 2019 Jan 31;44(1):e7.
doi: 10.5395/rde.2019.44.e7. eCollection 2019 Feb.

Endodontic biofilms: contemporary and future treatment options

Yeon-Jee Yoo  1 , Hiran Perinpanayagam  2 , Soram Oh  3 , A-Reum Kim  4 , Seung-Hyun Han  4 , Kee-Yeon Kum  1
Affiliations
Review

Endodontic biofilms: contemporary and future treatment options

Yeon-Jee Yoo et al. Restor Dent Endod. .

Abstract

Apical periodontitis is a biofilm-mediated infection. The biofilm protects bacteria from host defenses and increase their resistance to intracanal disinfecting protocols. Understanding the virulence of these endodontic microbiota within biofilm is essential for the development of novel therapeutic procedures for intracanal disinfection. Both the disruption of biofilms and the killing of their bacteria are necessary to effectively treat apical periodontitis. Accordingly, a review of endodontic biofilm types, antimicrobial resistance mechanisms, and current and future therapeutic procedures for endodontic biofilm is provided.

Keywords: Antimicrobial resistance; Endodontic biofilm; Intracanal disinfection; Lactobacillus; Lipoteichoic acid.

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Conflict of interest statement

Conflict of Interest: No potential conflict of interest relevant to this article was reported.

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