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. 1978 Jun 29;262(1):37-44.
doi: 10.1007/BF00455571.

T-cell function in atopic dermatitis. Controlled examination of concanavalin A dose-response relations in cultured lymphocytes

E Schöpf, A Kapp, C W Kim

T-cell function in atopic dermatitis. Controlled examination of concanavalin A dose-response relations in cultured lymphocytes

E Schöpf et al. Arch Dermatol Res. .

Abstract

The Concanavalin A (Con A) stimulation response of peripheral lymphocytes in vitro was found to be decreased statistically significant (alpha = 0.005) in patients with light atopic dermatitis, Strictly matched pairs were examined. Using ten graded concentrations of Con A, dose-response relations of the pairs were demonstrated, differences were more evident at lower suboptimal concentrations. Background DNA-synthesis of the patients was elevated.

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