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Comment
. 2019 Apr;597(8):2129-2130.
doi: 10.1113/JP277805. Epub 2019 Mar 18.

When bigger isn't better: understanding the anabolic resistance of obese skeletal muscle

Affiliations
Comment

When bigger isn't better: understanding the anabolic resistance of obese skeletal muscle

Cassidy Tinline-Goodfellow et al. J Physiol. 2019 Apr.
No abstract available

Keywords: Amino acids; Anabolic Resistance; Protein synthesis; Skeletal muscle; mTOR.

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References

    1. Abou Sawan S, van Vliet S, West DWD, Beals JW, Paluska SA, Burd NA & Moore DR (2018). Whole egg, but not egg white, ingestion induces mTOR colocalization with the lysosome after resistance exercise. Am J Physiol Cell Physiol, 315, C537–C543. - PMC - PubMed
    1. Beals JW, Skinner SK, McKenna CF, Poozhikunnel EG, Farooqi SA, van Vliet S, Martinez IG, Ulanov AV, Li Z, Paluska SA & Burd NA (2018). Altered anabolic signalling and reduced stimulation of myofibrillar protein synthesis after feeding and resistance exercise in people with obesity. J Physiol 596, 5119–5133. - PMC - PubMed
    1. Daemen S, Gemmink A, Brouwers B, Meex RCR, Huntjens PR, Schaart G, Moonen‐Kornips E, Jörgensen J, Hoeks J, Schrauwen P & Hesselink MKC (2018). Distinct lipid droplet characteristics and distribution unmask the apparent contradiction of the athlete's paradox. Mol Metab, 17, 71–81. - PMC - PubMed
    1. Damas F, Phillips SM, Libardi CA, Vechin FC, Lixandrao ME, Jannig PR, Costa LA, Bacurau AV, Snijders T, Parise G, Tricoli V, Roschel H & Ugrinowitsch C (2016). Resistance training‐induced changes in integrated myofibrillar protein synthesis are related to hypertrophy only after attenuation of muscle damage. J Physiol 594, 5209–5222. - PMC - PubMed
    1. Goodman CA, Mabrey DM, Frey JW, Miu MH, Schmidt EK, Pierre P & Hornberger TA (2011). Novel insights into the regulation of skeletal muscle protein synthesis as revealed by a new nonradioactive in vivo technique. FASEB J, 25, 1028–1039. - PMC - PubMed

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