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Book

Antihistamines

Khashayar Farzam  1 , Sarah Sabir  2 , Maria C. O'Rourke  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Antihistamines

Khashayar Farzam et al.
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Excerpt

Antihistamines are a pharmaceutical class of drugs that act to treat histamine-mediated conditions. There are two main classes of histamine receptors: H-1 receptors and H-2 receptors. Antihistamine drugs that bind to H-1 receptors are generally used to treat allergies and allergic rhinitis. Drugs that bind to H-2 receptors can treat upper gastrointestinal conditions that are caused by excessive stomach acid. This activity reviews the indications, contraindications, activity, adverse events, and other vital elements of antihistamine therapy in the clinical setting as relates to the essential points needed by members of an interprofessional team managing the care of patients with conditions that respond to histamine receptor blockade.

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Conflict of interest statement

Disclosure: Khashayar Farzam declares no relevant financial relationships with ineligible companies.

Disclosure: Sarah Sabir declares no relevant financial relationships with ineligible companies.

Disclosure: Maria O'Rourke declares no relevant financial relationships with ineligible companies.

References

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    1. Schaefer TS, Patel P, Zito PM. StatPearls [Internet] StatPearls Publishing; Treasure Island (FL): 2024. Mar 10, Antiemetic Histamine H1 Receptor Blockers. - PubMed
    1. Curto-Barredo L, Giménez-Arnau AM. Treatment of chronic spontaneous urticaria with an inadequate response to H1-antihistamine. G Ital Dermatol Venereol. 2019 Aug;154(4):444-456. - PubMed
    1. Kuna L, Jakab J, Smolic R, Raguz-Lucic N, Vcev A, Smolic M. Peptic Ulcer Disease: A Brief Review of Conventional Therapy and Herbal Treatment Options. J Clin Med. 2019 Feb 03;8(2) - PMC - PubMed
    1. Pirahanchi Y, Sharma S. StatPearls [Internet] StatPearls Publishing; Treasure Island (FL): 2023. Jul 11, Physiology, Bradykinin.

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