Antihistamines
- PMID: 30844215
- Bookshelf ID: NBK538188
Antihistamines
Excerpt
Antihistamines remain a cornerstone of therapy for allergic and acid-related disorders, yet evolving evidence continues to reshape their clinical use. This activity provides an in-depth review of the pharmacology, therapeutic applications, and safety considerations of H1 and H2 receptor antagonists—agents widely used across multiple care settings. Participants explore current understanding of histamine receptor physiology, mechanisms of action, and distinctions between first- and second-generation antihistamines, with emphasis on clinical decision-making for allergic rhinitis, chronic urticaria, and gastroesophageal reflux disease.
Copyright © 2025, StatPearls Publishing LLC.
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