Intraleaflet Hemorrhage and Iron-Dependent Pathomechanisms in Calcific Aortic Valve Disease: Epiphenomenon or Major Actor?

Affiliations

¹ Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center NRW, University Hospital Ruhr-University Bochum, Bad Oeynhausen, Germany. Electronic address: mdeutsch@hdz-nrw.de.
² Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center NRW, University Hospital Ruhr-University Bochum, Bad Oeynhausen, Germany.

Free article

Editorial

Marcus-André Deutsch et al. J Am Coll Cardiol. 2019.

Free article

. 2019 Mar 12;73(9):1055-1058.

doi: 10.1016/j.jacc.2018.12.041.

¹ Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center NRW, University Hospital Ruhr-University Bochum, Bad Oeynhausen, Germany. Electronic address: mdeutsch@hdz-nrw.de.
² Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center NRW, University Hospital Ruhr-University Bochum, Bad Oeynhausen, Germany.

No abstract available

Keywords: calcific aortic valve disease; leaflet hemorrhage; pathogenesis.

Comment on

Relationship of Iron Deposition to Calcium Deposition in Human Aortic Valve Leaflets.
Morvan M, Arangalage D, Franck G, Perez F, Cattan-Levy L, Codogno I, Jacob-Lenet MP, Deschildre C, Choqueux C, Even G, Michel JB, Bäck M, Messika-Zeitoun D, Nicoletti A, Caligiuri G, Laschet J. Morvan M, et al. J Am Coll Cardiol. 2019 Mar 12;73(9):1043-1054. doi: 10.1016/j.jacc.2018.12.042. J Am Coll Cardiol. 2019. PMID: 30846099