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. 2019 Jan 9;7(2):397-400.
doi: 10.1002/ccr3.1986. eCollection 2019 Feb.

Ventricular septal rupture following myocardial infarction: A potentially fatal complication

Athanasios Saplaouras  1 , Antigoni Sakellaropoulou  1 , Panagiotis Mililis  1 , George Bazoukis  1 , Angelos-Michail Kolokathis  1 , Eleni Konstantinidou  1 , Aikaterini Anagnostou  1 , Niki Panagopoulou  1 , Konstantinos Vlachos  1 , Ioannis Lakoumentas  1 , Antonios Sideris  1
Affiliations

Ventricular septal rupture following myocardial infarction: A potentially fatal complication

Athanasios Saplaouras et al. Clin Case Rep. .

Abstract

Mechanical complications of acute myocardial infarction include ventricular septal rupture (VSR), free wall rupture, and ischemic mitral regurgitation. Postinfarction VSR is a rare but serious complication of myocardial infarction. VSR has a lower incidence in the era of new reperfusion therapies. However, clinicians should be aware of this potentially fatal complication as the mortality remains extremely high. Early diagnosis and treatment are the cornerstones of achieving a better outcome.

Keywords: complication; infraction; myocardial; rupture; septal; ventricular.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Electrocardiogram of the patient at the time of admission showed second‐degree atrioventricular block (2:1), and Q‐waves in the inferior lead with ST‐segment elevation >2 mm
Figure 2
Figure 2
Coronary angiography (A) LAO cranial view: right coronary artery (RCA) with subtotal occlusion in the mid‐segment. (B) RAO caudal view: left anterior descending artery (LAD) with a proximal and mid 80% stenoses, left circumflex artery (LCx) with a proximal 70% stenosis and mid 80% stenosis
Figure 3
Figure 3
Presence of ventricular septal defect as seen in 2‐dimensional transthoracic echocardiography in parasternal short‐axis view (PTSAX)
See this image and copyright information in PMC

References

    1. Jones BM, Kapadia SR, Smedira NG, et al. Ventricular septal rupture complicating acute myocardial infarction: a contemporary review. Eur Heart J. 2014;35(31):2060‐2068. - PubMed
    1. Birnbaum Y, Fishbein MC, Blanche C, Siegel RJ. Ventricular septal rupture after acute myocardial infarction. N Engl J Med. 2002;347(18):1426‐1432. - PubMed
    1. Crenshaw BS, Granger CB, Birnbaum Y, et al. Risk factors, angiographic patterns, and outcomes in patients with ventricular septal defect complicating acute myocardial infarction. GUSTO‐I (Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries) Trial Investigators. Circulation. 2000;101(1):27‐32. - PubMed
    1. Menon V, Webb JG, Hillis LD, et al. Outcome and profile of ventricular septal rupture with cardiogenic shock after myocardial infarction: a report from the SHOCK Trial Registry. SHould we emergently revascularize Occluded Coronaries in cardiogenic shocK? J Am Coll Cardiol. 2000;36(3 Suppl A):1110‐1116. - PubMed
    1. Faletra F, Moreo A, Frigerio M, et al. Usefulness of color Doppler in the diagnosis of ventricular septal rupture after myocardial infarction. G Ital Cardiol. 1990;20(12):1101‐1106. - PubMed

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