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Review
. 2019 Feb;5(1):5-8.
doi: 10.15420/cfr.2018.43.1.

The New Heart Failure Association Definition of Advanced Heart Failure

Marco Metra  1 , Elisabetta Dinatolo  1 , Nicolò Dasseni  1
Affiliations
Review

The New Heart Failure Association Definition of Advanced Heart Failure

Marco Metra et al. Card Fail Rev. 2019 Feb.

Abstract

The clinical course of heart failure is characterised by progressive worsening of cardiac function and symptoms. Patients progress to a condition where traditional treatment is no longer effective and advanced therapies, such as mechanical circulatory support, heart transplantation and/or palliative care, are needed. This condition is called advanced chronic heart failure. The Heart Failure Association first defined it in 2007 and this definition was updated in 2018. The updated version emphasises the role of comorbidities, including tachyarrhythmias, and the role of heart failure with preserved ejection fraction. Improvements in mechanical circulatory support technology and better disease management programmes are major advances and are radically changing the management of these patients.

Keywords: Heart failure; advanced heart failure; heart transplantation; mechanical circulatory support; prognosis.

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Conflict of interest statement

Disclosure: MM has received honoraria as participant in clinical trials committees or to advisory boards from Amgen, Bayer, Fresenius, Novartis and Servier. The other authors have no conflict of interest to declare.

References

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