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Case Reports

. 2019 Aug 27;57(9):e218-e221.

doi: 10.1515/cclm-2019-0090.

Lesson from inappropriate TSH-receptor antibody measurement in hypothyroidism: case series and literature review

Affiliations

Affiliations

¹ Department of Endocrinology, Diabetology and Metabolism, CHU Lille, Lille, France.
² CHU Rennes, Department of Biochemistry, Rennes, France.
³ University of Rennes 1, Faculty of Medicine, Rennes, France.
⁴ CHU Lille, Immunoanalysis Center, Biology and Pathology Center, Lille, France.
⁵ CH Bethune, Endocrinology, Diabetology and Metabolism, Bethune, France.
⁶ Medical Practice Endocrinology, Roubaix, France.

PMID: 30849043
DOI: 10.1515/cclm-2019-0090

Case Reports

Lesson from inappropriate TSH-receptor antibody measurement in hypothyroidism: case series and literature review

Arnaud Jannin et al. Clin Chem Lab Med. 2019.

. 2019 Aug 27;57(9):e218-e221.

doi: 10.1515/cclm-2019-0090.

Affiliations

¹ Department of Endocrinology, Diabetology and Metabolism, CHU Lille, Lille, France.
² CHU Rennes, Department of Biochemistry, Rennes, France.
³ University of Rennes 1, Faculty of Medicine, Rennes, France.
⁴ CHU Lille, Immunoanalysis Center, Biology and Pathology Center, Lille, France.
⁵ CH Bethune, Endocrinology, Diabetology and Metabolism, Bethune, France.
⁶ Medical Practice Endocrinology, Roubaix, France.

PMID: 30849043
DOI: 10.1515/cclm-2019-0090

No abstract available

Keywords: autoantibody; autoimmune thyroid disease; bioassay; severe hypothyroidism; thyrotropin (TSH)-receptor blocking antibodies.

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References

1. Garber J, Cobin RH, Gharib H, Hennessey JV, Klein I, Mechanick JI, et al. Clinical practice guidelines for hypothyroidism in adults: cosponsored by American Association of Clinical Endocrinologists and the American Thyroid Association. Endocr Pract 2012;18:988–1028.
1. McLachlan SM, Rapoport B. Thyrotropin-blocking autoantibodies and thyroid stimulating autoantibodies: potential mechanisms involved in the pendulum swinging from hypothyroidism to hyperthyroidism or vice versa. Thyroid 2013;23:14–24.
1. Diana T, Krause J, Olivo PD, König J, Kanitz M, Decallonne B, et al. Prevalence and clinical relevance of thyroid stimulating hormone receptor-blocking antibodies in autoimmune thyroid disease. Clin Exp Immunol 2017;189:304–9.
1. Diana T, Olivo PD, Kahaly GJ. Thyrotropin receptor blocking antibodies. Horm Metab Res 2018;50:853–62.
1. Massart C, Orgiazzi J, Maugendre D. Clinical validity of a new commercial method for detection of TSH-receptor bindingantibodies in sera from patients with Graves’ disease treated with antithyroid drugs. Clin Chim Acta 2001;304:39–47.

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