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Case Reports
. 2019 Aug 27;57(9):e218-e221.
doi: 10.1515/cclm-2019-0090.

Lesson from inappropriate TSH-receptor antibody measurement in hypothyroidism: case series and literature review

Arnaud Jannin  1 , Lucas Peltier  2   3 , Michèle d'Herbomez  4 , Frédérique Defrance  5 , Sophie Marcelli  6 , Adrien Ben Hamou  1 , Linda Humbert  1 , Jean-Louis Wémeau  1 , Marie-Christine Vantyghem  1 , Stéphanie Espiard  1
Affiliations
Case Reports

Lesson from inappropriate TSH-receptor antibody measurement in hypothyroidism: case series and literature review

Arnaud Jannin et al. Clin Chem Lab Med. .
No abstract available

Keywords: autoantibody; autoimmune thyroid disease; bioassay; severe hypothyroidism; thyrotropin (TSH)-receptor blocking antibodies.

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References

    1. Garber J, Cobin RH, Gharib H, Hennessey JV, Klein I, Mechanick JI, et al. Clinical practice guidelines for hypothyroidism in adults: cosponsored by American Association of Clinical Endocrinologists and the American Thyroid Association. Endocr Pract 2012;18:988–1028.
    1. McLachlan SM, Rapoport B. Thyrotropin-blocking autoantibodies and thyroid stimulating autoantibodies: potential mechanisms involved in the pendulum swinging from hypothyroidism to hyperthyroidism or vice versa. Thyroid 2013;23:14–24.
    1. Diana T, Krause J, Olivo PD, König J, Kanitz M, Decallonne B, et al. Prevalence and clinical relevance of thyroid stimulating hormone receptor-blocking antibodies in autoimmune thyroid disease. Clin Exp Immunol 2017;189:304–9.
    1. Diana T, Olivo PD, Kahaly GJ. Thyrotropin receptor blocking antibodies. Horm Metab Res 2018;50:853–62.
    1. Massart C, Orgiazzi J, Maugendre D. Clinical validity of a new commercial method for detection of TSH-receptor bindingantibodies in sera from patients with Graves’ disease treated with antithyroid drugs. Clin Chim Acta 2001;304:39–47.

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