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Comment
. 2019 Mar 7;24(3):355-356.
doi: 10.1016/j.stem.2019.02.007.

Dynamic Changes in the Niche with N-Cadherin Revisited: The HSC "Niche Herein"

Ayako Nakamura-Ishizu  1 , Toshio Suda  2
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Dynamic Changes in the Niche with N-Cadherin Revisited: The HSC "Niche Herein"

Ayako Nakamura-Ishizu et al. Cell Stem Cell. .
Free article

Abstract

Recently in Cell Reports, Zhao et al. report that chemo-resistant (reserve) hematopoietic stem cells (HSCs) are maintained in the endosteal niche under the influence of N-cadherin+ bone-lining cells (Zhao et al., 2019). These findings further indicate that niches for bone marrow HSCs may differ dynamically during physiological and stress hematopoiesis.

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