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. 2019 Mar 7;73(5):866-868.
doi: 10.1016/j.molcel.2019.02.021.

ADAR1: A New Target for Immuno-oncology Therapy

Amruta Bhate  1 , Tao Sun  1 , Jin Billy Li  2
Affiliations
Free article

ADAR1: A New Target for Immuno-oncology Therapy

Amruta Bhate et al. Mol Cell. .
Free article

Abstract

Three recent studies by Ishizuka et al. (2019), Liu et al. (2019), and Gannon et al. (2018) show that deleting RNA editing enzyme ADAR1 could induce higher cell lethality and render tumor cells more vulnerable to immunotherapy, pinpointing ADAR1 as a new immuno-oncology target.

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