Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Apr;37(2):215-228.
doi: 10.1016/j.det.2018.12.003. Epub 2019 Feb 14.

Treatment Update of Autoimmune Blistering Diseases

Khalaf Kridin  1 , Christine Ahn  2 , William C Huang  2 , Ahmed Ansari  3 , Naveed Sami  4
Affiliations
Review

Treatment Update of Autoimmune Blistering Diseases

Khalaf Kridin et al. Dermatol Clin. 2019 Apr.

Abstract

The treatment of refractory autoimmune blistering diseases (AIBDs) has always been a challenge. Because randomized controlled trials are lacking, treatment has been based on analysis of anecdotal data. The last 2 decades has seen the use of rituximab become a conventional treatment in the therapeutic armamentarium of AIBDs, leading to its Food and Drug Administration indication for pemphigus vulgaris in 2018. We review the current updated data on the use of rituximab including dosing, protocols, and its role in the algorithm of AIBDs. In addition, we discuss several promising novel emerging therapeutic agents for AIBDs.

Keywords: Autoimmune blistering diseases; Emerging; Rituximab; Treatment.

PubMed Disclaimer

MeSH terms