Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 May-Jun:40:41-46.
doi: 10.1016/j.carpath.2019.02.002. Epub 2019 Feb 10.

A plasma cell-based pericardial effusion leading to tamponade in a patient with multiple myeloma - a case report and review of the literature

Travis M Skipina  1 , David C Sane  2 , Charles Cui  2 , Steven Song  2 , Stephen G Phillips  2 , Robert W Jarrett  3
Affiliations
Case Reports

A plasma cell-based pericardial effusion leading to tamponade in a patient with multiple myeloma - a case report and review of the literature

Travis M Skipina et al. Cardiovasc Pathol. 2019 May-Jun.

Abstract

A rare case of extramedullary multiple myeloma causing cardiac tamponade secondary to a plasma cell-based pericardial effusion is described. A systematic search using PubMed (National Library of Medicine) was used to identify a further 27 cases dating back to 1970. Case characteristics, treatment strategies, and survival time following tamponade are discussed. Linear regression demonstrated a weak but statistically significant correlation between survival time following tamponade and treatment with systemic chemotherapy and steroids (β=16.8 weeks, P=.009). However, this manifestation of extramedullary multiple myeloma still conveys a dismal prognosis with a median survival following tamponade of only 6 weeks based on our review.

Keywords: Cardiac tamponade; Multiple myeloma; Pericardial effusion; Plasma cell; Plasmacytoma.

PubMed Disclaimer

MeSH terms

LinkOut - more resources