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Review
. 2019 Dec;23(6):497-506.
doi: 10.1111/1744-9987.12800. Epub 2019 Apr 23.

New-Onset Diabetes Mellitus in Peritoneal Dialysis and Hemodialysis Patients: Frequency, Risk Factors, and Prognosis-A Review

Rajashri Yarragudi  1 , Alois Gessl  2 , Andreas Vychytil  1
Affiliations
Review

New-Onset Diabetes Mellitus in Peritoneal Dialysis and Hemodialysis Patients: Frequency, Risk Factors, and Prognosis-A Review

Rajashri Yarragudi et al. Ther Apher Dial. 2019 Dec.

Abstract

New-onset diabetes mellitus (NODM) is observed in both hemodialysis (HD) and peritoneal dialysis (PD) patients. The prevalence of NODM in dialysis patients is slightly higher compared to subjects of the general population. Based on currently published data there is no convincing evidence that the risk of NODM is different between HD and PD patients. Data on the effect of glucose load on risk of NODM in dialysis patients remain controversial. PD modality (automated or continuous ambulatory PD) has no significant influence on NODM incidence. Chronic inflammation is associated with NODM in dialysis patients. Reported differences in NODM between PD and HD patients are possibly also influenced by differences in demographic factors between these patient groups. Mortality in NODM patients is lower than mortality in patients with preexisting DM. This may be partly explained by the younger age and lower number of comorbidities in patients with NODM.

Keywords: Diabetes; Glucose Load; Hemodialysis; New-Onset Diabetes Mellitus; Peritoneal Dialysis.

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Conflict of interest statement

None.

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