Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Mar 19;8(6):e010972.
doi: 10.1161/JAHA.118.010972.

His Bundle Pacing: A New Strategy for Physiological Ventricular Activation

Affiliations
Review

His Bundle Pacing: A New Strategy for Physiological Ventricular Activation

Andrew J M Lewis et al. J Am Heart Assoc. .

Erratum in

No abstract available

Keywords: His bundle; pacemaker; resynchronization.

PubMed Disclaimer

Figures

Figure 1
Figure 1
ECGs from the same patient demonstrating selective and nonselective ventricular capture according to pacing energy. Selective capture is seen at 4 V at 1 ms while nonselective capture occurs higher output (8 V at 1 ms; note the pseudodelta wave and absence of stimulus‐QRS [S‐QRS] isoelectric interval in nonselective capture). Depending on the lead position and His bundle anatomy, some patients (the majority in many series) will exhibit only nonselective capture regardless of pacemaker output. H‐QRS indicates His electrogram to QRS interval.
Figure 2
Figure 2
Correction of right bundle branch block (RBBB)/left anterior fascicular block (LAFB) with His bundle pacing (HBP) with nonselective capture, also enabling restoration of shorter atrioventricular (AV) conduction. The mechanisms by which HBP is able to correct bundle branch block remain contentious but are thought to include recruitment of fibers distal to the site of delay and improved capture relating to higher pacing output and suggest that bundle branch “block” is relative.

Similar articles

Cited by

References

    1. Tse H‐F, Lau C‐P. Long‐term effect of right ventricular pacing on myocardial perfusion and function. J Am Coll Cardiol. 1997;29:744–749. - PubMed
    1. Kanzaki H, Bazaz R, Schwartzman D, Dohi K, Sade LE, Gorcsan J. A mechanism for immediate reduction in mitral regurgitation after cardiac resynchronization therapy: insights from mechanical activation strain mapping. J Am Coll Cardiol. 2004;44:1619–1625. - PubMed
    1. Thambo J‐B, Bordachar P, Garrigue S, Lafitte S, Sanders P, Reuter S, Girardot R, Crepin D, Reant P, Roudaut R. Detrimental ventricular remodeling in patients with congenital complete heart block and chronic right ventricular apical pacing. Circulation. 2004;110:3766–3772. - PubMed
    1. Wilkoff BL, Cook JR, Epstein AE, Greene HL, Hallstrom AP, Hsia H, Kutalek SP, Sharma A. Dual‐chamber pacing or ventricular backup pacing in patients with an implantable defibrillator: the Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial. JAMA. 2002;288:3115–3123. - PubMed
    1. Sharma AD, Rizo‐Patron C, Hallstrom AP, O'Neill GP, Rothbart S, Martins JB, Roelke M, Steinberg JS, Greene HL; Investigators D . Percent right ventricular pacing predicts outcomes in the DAVID trial. Heart Rhythm. 2005;2:830–834. - PubMed

Publication types

MeSH terms