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. 2019 Oct 30;69(10):1801-1804.
doi: 10.1093/cid/ciz189.

Are Many Patients Diagnosed With Healthcare-associated Clostridioides difficile Infections Colonized With the Infecting Strain on Admission?

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Are Many Patients Diagnosed With Healthcare-associated Clostridioides difficile Infections Colonized With the Infecting Strain on Admission?

Melany Gonzalez-Orta et al. Clin Infect Dis. .

Abstract

In a cohort of 480 patients admitted to an acute care hospital, 68 (14%) had positive perirectal cultures for toxigenic Clostridioides difficile on admission. Of the 11 patients (2%) diagnosed with healthcare-associated C. difficile infections, 3 (27%) had genetically related admission and infection isolates, based on whole-genome sequencing.

Keywords: Clostridioides difficile; colonization; healthcare-associated; infection control; whole genome sequencing.

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