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Book

Heparin

Preeti Patel, Davis Huang  1
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Heparin

Preeti Patel et al.
Free Books & Documents

Excerpt

Unfractionated heparin is an anticoagulant used for the prevention and treatment of thrombotic events, including deep vein thrombosis, pulmonary embolism, and atrial fibrillation. Heparin is also indicated for preventing clot formation during procedures such as cardiac surgery, extracorporeal circulation, dialysis, and continuous renal replacement therapy. In addition to approved indications, heparin is widely utilized in hospitals for various off-label uses.

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Conflict of interest statement

Disclosure: Preeti Patel declares no relevant financial relationships with ineligible companies.

Disclosure: Davis Huang declares no relevant financial relationships with ineligible companies.

References

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    1. Mulloy B, Hogwood J, Gray E, Lever R, Page CP. Pharmacology of Heparin and Related Drugs. Pharmacol Rev. 2016 Jan;68(1):76-141. - PubMed
    1. Hirsh J, Anand SS, Halperin JL, Fuster V, American Heart Association AHA Scientific Statement: Guide to anticoagulant therapy: heparin: a statement for healthcare professionals from the American Heart Association. Arterioscler Thromb Vasc Biol. 2001 Jul;21(7):E9-9. - PubMed
    1. Hemker HC. A century of heparin: past, present and future. J Thromb Haemost. 2016 Dec;14(12):2329-2338. - PubMed
    1. Shore-Lesserson L, Baker RA, Ferraris VA, Greilich PE, Fitzgerald D, Roman P, Hammon JW. The Society of Thoracic Surgeons, The Society of Cardiovascular Anesthesiologists, and The American Society of ExtraCorporeal Technology: Clinical Practice Guidelines-Anticoagulation During Cardiopulmonary Bypass. Ann Thorac Surg. 2018 Feb;105(2):650-662. - PubMed

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